--- title: G. Methylation author: Martin Morgan (mtmorgan@fredhutch.org) date: "`r Sys.Date()`" output: BiocStyle::html_document: toc: true vignette: > %\VignetteIndexEntry{G. Methylation} %\VignetteEngine{knitr::rmarkdown} \usepackage[utf8]{inputenc} --- ```{r style, echo=FALSE, results='asis'} BiocStyle::markdown() ``` # Motivation # Work flow & statistical issues ## Methylation microarrays and differentially methylated probesets ## Differential methylated regions Hunting bumps Testing significance # Practical: [minfi](http://bioconductor.org/packages/devel/bioc/html/minfi.html)