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BindingSiteFinder

This is the development version of BindingSiteFinder; for the stable release version, see BindingSiteFinder.

Binding site defintion based on iCLIP data


Bioconductor version: Development (3.19)

Precise knowledge on the binding sites of an RNA-binding protein (RBP) is key to understand (post-) transcriptional regulatory processes. Here we present a workflow that describes how exact binding sites can be defined from iCLIP data. The package provides functions for binding site definition and result visualization. For details please see the vignette.

Author: Mirko Brüggemann [aut, cre] , Kathi Zarnack [aut]

Maintainer: Mirko Brüggemann <mirko.brueggemann at mail.de>

Citation (from within R, enter citation("BindingSiteFinder")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("BindingSiteFinder")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews Coverage, DataImport, FunctionalGenomics, GeneExpression, GeneRegulation, Sequencing, Software
Version 2.1.0
In Bioconductor since BioC 3.14 (R-4.1) (2.5 years)
License Artistic-2.0
Depends GenomicRanges, R (>= 4.2)
Imports tidyr, tibble, plyr, matrixStats, stats, ggplot2, methods, rtracklayer, S4Vectors, ggforce, GenomeInfoDb, ComplexHeatmap, RColorBrewer, lifecycle, rlang, forcats, dplyr, GenomicFeatures, IRanges, kableExtra, ggdist
System Requirements
URL
Bug Reports https://github.com/ZarnackGroup/BindingSiteFinder/issues
See More
Suggests testthat, BiocStyle, knitr, rmarkdown, GenomicAlignments, scales, Gviz, xlsx, GGally, patchwork, viridis, ggplotify, SummarizedExperiment, DESeq2, ggpointdensity, ggrastr, ashr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/BindingSiteFinder
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/BindingSiteFinder
Package Short Url https://bioconductor.org/packages/BindingSiteFinder/
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