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diffcyt

This is the development version of diffcyt; for the stable release version, see diffcyt.

Differential discovery in high-dimensional cytometry via high-resolution clustering


Bioconductor version: Development (3.19)

Statistical methods for differential discovery analyses in high-dimensional cytometry data (including flow cytometry, mass cytometry or CyTOF, and oligonucleotide-tagged cytometry), based on a combination of high-resolution clustering and empirical Bayes moderated tests adapted from transcriptomics.

Author: Lukas M. Weber [aut, cre]

Maintainer: Lukas M. Weber <lmweberedu at gmail.com>

Citation (from within R, enter citation("diffcyt")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("diffcyt")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews CellBasedAssays, CellBiology, Clustering, FeatureExtraction, FlowCytometry, ImmunoOncology, Proteomics, SingleCell, Software
Version 1.23.1
In Bioconductor since BioC 3.7 (R-3.5) (6 years)
License MIT + file LICENSE
Depends R (>= 3.4.0)
Imports flowCore, FlowSOM, SummarizedExperiment, S4Vectors, limma, edgeR, lme4, multcomp, dplyr, tidyr, reshape2, magrittr, stats, methods, utils, grDevices, graphics, ComplexHeatmap, circlize, grid
System Requirements
URL https://github.com/lmweber/diffcyt
Bug Reports https://github.com/lmweber/diffcyt/issues
See More
Suggests BiocStyle, knitr, rmarkdown, testthat, HDCytoData, CATALYST
Linking To
Enhances
Depends On Me censcyt, cytofWorkflow
Imports Me CyTOFpower, treeclimbR, treekoR
Suggests Me CATALYST
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/diffcyt
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/diffcyt
Package Short Url https://bioconductor.org/packages/diffcyt/
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