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Accurate consensus sequence from nanopore reads of a gene library

Bioconductor version: Development (3.19)

Accurate consensus sequence from nanopore reads of a DNA gene library. SINGLe corrects for systematic errors in nanopore sequencing reads of gene libraries and it retrieves true consensus sequences of variants identified by a barcode, needing only a few reads per variant. More information in preprint doi:

Author: Rocio Espada [aut, cre]

Maintainer: Rocio Espada <rocio.espada at>

Citation (from within R, enter citation("single")):


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biocViews Sequencing, Software
Version 1.7.0
In Bioconductor since BioC 3.15 (R-4.2) (2 years)
License MIT + file LICENSE
Depends R (>= 4.0)
Imports Biostrings, BiocGenerics, dplyr, GenomicAlignments, IRanges, methods, reshape2, rlang, Rsamtools, stats, stringr, tidyr, utils
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