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Cell type-specific deconvolution of heterogeneous tumor samples with two or three components using expression data from RNAseq or microarray platforms

Bioconductor version: Release (3.18)

DeMixT is a software package that performs deconvolution on transcriptome data from a mixture of two or three components.

Author: Zeya Wang <zw17.rice at gmail.com>, Shaolong Cao<scao at mdanderson.org>, Wenyi Wang <wwang7 at at mdanderson.org>

Maintainer: Shuai Guo <shuai.guo at uth.tmc.edu>

Citation (from within R, enter citation("DeMixT")):


To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

DeMixT.Rmd HTML R Script
Reference Manual PDF


biocViews Classification, Coverage, GeneExpression, Microarray, Sequencing, Software, StatisticalMethod, TissueMicroarray
Version 1.18.0
In Bioconductor since BioC 3.9 (R-3.6) (5 years)
License GPL-3
Depends R (>= 3.6.0), parallel, Rcpp (>= 1.0.0), SummarizedExperiment, knitr, KernSmooth, matrixcalc, rmarkdown, DSS, dendextend, psych, sva
Imports matrixStats, stats, truncdist, base64enc, ggplot2
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DeMixT_1.18.0.tar.gz
Windows Binary DeMixT_1.18.0.zip
macOS Binary (x86_64) DeMixT_1.18.0.tgz
macOS Binary (arm64) DeMixT_1.18.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/DeMixT
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DeMixT
Bioc Package Browser https://code.bioconductor.org/browse/DeMixT/
Package Short Url https://bioconductor.org/packages/DeMixT/
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