Registration Open for Bioc2024 July 24-26


Collection and implementation of public transcriptional cancer signatures

Bioconductor version: Release (3.19)

signifinder is an R package for computing and exploring a compendium of tumor signatures. It allows to compute a variety of signatures, based on gene expression values, and return single-sample scores. Currently, signifinder contains more than 60 distinct signatures collected from the literature, relating to multiple tumors and multiple cancer processes.

Author: Stefania Pirrotta [cre, aut] , Enrica Calura [aut]

Maintainer: Stefania Pirrotta <stefania.pirrotta at>

Citation (from within R, enter citation("signifinder")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

signifinder vignette HTML R Script
Reference Manual PDF


biocViews BiomedicalInformatics, GeneExpression, GeneSignaling, GeneTarget, ImmunoOncology, Microarray, RNASeq, ReportWriting, SingleCell, Software, Spatial, Visualization
Version 1.6.0
In Bioconductor since BioC 3.16 (R-4.2) (1.5 years)
License AGPL-3
Depends R (>= 4.3.0)
Imports AnnotationDbi, BiocGenerics, ComplexHeatmap, consensusOV, cowplot, DGEobj.utils, dplyr, ensembldb, ggplot2, ggridges, GSVA, IRanges, magrittr, matrixStats, maxstat, methods, openair,, patchwork, RColorBrewer, TxDb.Hsapiens.UCSC.hg19.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, sparrow, SpatialExperiment, stats, SummarizedExperiment, survival, survminer, viridis
System Requirements
Bug Reports
See More
Suggests BiocStyle, edgeR, grid, kableExtra, knitr, limma, testthat (>= 3.0.0)
Linking To
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package signifinder_1.6.0.tar.gz
Windows Binary
macOS Binary (x86_64) signifinder_1.6.0.tgz
macOS Binary (arm64) signifinder_1.6.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
Bioc Package Browser
Package Short Url
Package Downloads Report Download Stats