Contents

1 Introduction

1.1 The Comparative Toxicogenomics Database

The Comparative Toxicogenomics Database (CTDbase; http://ctdbase.org) is a public resource for toxicogenomic information manually curated from the peer-reviewed scientific literature, providing key information about the interactions of environmental chemicals with gene products and their effect on human disease [1][2].

1.2 CTDquerier R package

CTDquerier is an R package that allows to R users to download basic data from CTDbase about genes, chemicals and diseases. Once the userโ€™s input is validated allows to query CTDbase to download the information of the given input from the other modules.

2 Quering The Comparative Toxicogenomics Database

CTDbase offers a public web-based interface that includes basic and advanced query options to access data for sequences, references, and toxic agents, and a platform for analysis sequences.

2.2 Batch Query

The Batch Query tool (http://ctdbase.org/tools/batchQuery.go) is a provided by CTDbase and allows to download custom data associated with a set of chemicals, diseases and genes amount others.