Changes in version 2.21.1 o From Travis-CI to Github Actions Changes in version 2.9.1 o Minor update to enhance compatibility with R 4.0.0 Changes in version 2.8.1 o Minor fix on documentation Changes in version 2.7.7 o RNA Seq validation o Random restart on Hill Climbing added to CAPRI algorithm o Minor fixes to algorithms and error model Changes in version 2.7.3 o Assignment to .GlobalEnv removed Changes in version 2.6.1 o Last stable releade with bugfix Changes in version 2.4.3 o New algorithms: Edmonds, Gabow, Chow-Liu and Prim. o New scores: PMI, CPMI, MI o A better bootstrap implementation Changes in version 2.4.2 o Implementation of maximum spanning tree algorithms. o Implementation of a noise model for cumulative phenomena. Changes in version 2.4.1 o A better implementation of remove.cycles. Changes in version 2.4.0 o New statistics available for model confidence via cross-validation routines. New algorithms based on Minimum Spanning Tree extraction. Changes in version 2.0.0 o Released in summer 2015 on our GitHUB, will replace the Bioconductor version in autumn 2015. This version is parallel, includes also the CAPRI algorithm, supports common input formats such as GISTIC (for Copy Number Variants), MAF (for mutations' annotation), supports TCGA samples editing and queries to the CBio portal. This version comes with new plotting capabilities, and a general from-scratch design. It is not compatible with previous releases. Changes in version 1.0.0 o Released in mid 2014 includes CAPRESE algorithm. It is now outdated and no more maintained.