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This is the development version of DMRcaller; for the stable release version, see DMRcaller.

Differentially Methylated Regions caller

Bioconductor version: Development (3.20)

Uses Bisulfite sequencing data in two conditions and identifies differentially methylated regions between the conditions in CG and non-CG context. The input is the CX report files produced by Bismark and the output is a list of DMRs stored as GRanges objects.

Author: Nicolae Radu Zabet <n.r.zabet at>, Jonathan Michael Foonlan Tsang <jmft2 at>, Alessandro Pio Greco <apgrec at> and Ryan Merritt <rmerri at>

Maintainer: Nicolae Radu Zabet <n.r.zabet at>

Citation (from within R, enter citation("DMRcaller")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

DMRcaller PDF R Script
Reference Manual PDF


biocViews Coverage, DNAMethylation, DifferentialMethylation, Sequencing, Software
Version 1.37.0
In Bioconductor since BioC 3.1 (R-3.2) (9 years)
License GPL-3
Depends R (>= 3.5), GenomicRanges, IRanges, S4Vectors(>= 0.23.10)
Imports parallel, Rcpp, RcppRoll, betareg, grDevices, graphics, methods, stats, utils
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Suggests knitr, RUnit, BiocGenerics
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Follow Installation instructions to use this package in your R session.

Source Package DMRcaller_1.37.0.tar.gz
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macOS Binary (x86_64) DMRcaller_1.37.0.tgz
macOS Binary (arm64) DMRcaller_1.37.0.tgz
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Source Repository (Developer Access) git clone
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