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This is the development version of ReactomePA; for the stable release version, see ReactomePA.

Reactome Pathway Analysis

Bioconductor version: Development (3.19)

This package provides functions for pathway analysis based on REACTOME pathway database. It implements enrichment analysis, gene set enrichment analysis and several functions for visualization.

Author: Guangchuang Yu [aut, cre], Vladislav Petyuk [ctb]

Maintainer: Guangchuang Yu <guangchuangyu at gmail.com>

Citation (from within R, enter citation("ReactomePA")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

An R package for Reactome Pathway Analysis HTML R Script
Reference Manual PDF


biocViews Annotation, GeneSetEnrichment, MultipleComparison, Pathways, Reactome, Software, Visualization
Version 1.47.0
In Bioconductor since BioC 2.10 (R-2.15) (12 years)
License GPL-2
Depends R (>= 3.4.0)
Imports AnnotationDbi, DOSE(>= 3.5.1), enrichplot, ggplot2 (>= 3.3.5), ggraph, reactome.db, igraph, graphite, gson
System Requirements
URL https://yulab-smu.top/biomedical-knowledge-mining-book/
Bug Reports https://github.com/GuangchuangYu/ReactomePA/issues
See More
Suggests BiocStyle, clusterProfiler, knitr, rmarkdown, org.Hs.eg.db, prettydoc, testthat
Linking To
Depends On Me maEndToEnd
Imports Me bioCancer, ExpHunterSuite, miRSM, miRspongeR, Pigengene, scTensor
Suggests Me CBNplot, ChIPseeker, CINdex, cola, GRaNIE, scGPS
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package ReactomePA_1.47.0.tar.gz
Windows Binary ReactomePA_1.47.0.zip
macOS Binary (x86_64) ReactomePA_1.47.0.tgz
macOS Binary (arm64) ReactomePA_1.47.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/ReactomePA
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/ReactomePA
Bioc Package Browser https://code.bioconductor.org/browse/ReactomePA/
Package Short Url https://bioconductor.org/packages/ReactomePA/
Package Downloads Report Download Stats