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ASSET

An R package for subset-based association analysis of heterogeneous traits and subtypes


Bioconductor version: Release (3.18)

An R package for subset-based analysis of heterogeneous traits and disease subtypes. The package allows the user to search through all possible subsets of z-scores to identify the subset of traits giving the best meta-analyzed z-score. Further, it returns a p-value adjusting for the multiple-testing involved in the search. It also allows for searching for the best combination of disease subtypes associated with each variant.

Author: Samsiddhi Bhattacharjee [aut, cre], Guanghao Qi [aut], Nilanjan Chatterjee [aut], William Wheeler [aut]

Maintainer: Samsiddhi Bhattacharjee <sb1 at nibmg.ac.in>

Citation (from within R, enter citation("ASSET")):

Installation

To install this package, start R (version "4.3") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ASSET")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ASSET")
ASSET Vignette PDF R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews GenomeWideAssociation, MultipleComparison, SNP, Software, StatisticalMethod
Version 2.20.0
In Bioconductor since BioC 2.13 (R-3.0) (10.5 years)
License GPL-2 + file LICENSE
Depends R (>= 3.5.0), stats, graphics
Imports MASS, msm, rmeta
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Suggests RUnit, BiocGenerics, knitr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package ASSET_2.20.0.tar.gz
Windows Binary ASSET_2.20.0.zip
macOS Binary (x86_64) ASSET_2.20.0.tgz
macOS Binary (arm64) ASSET_2.20.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/ASSET
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/ASSET
Bioc Package Browser https://code.bioconductor.org/browse/ASSET/
Package Short Url https://bioconductor.org/packages/ASSET/
Package Downloads Report Download Stats