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DeMAND

DeMAND


Bioconductor version: Release (3.18)

DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.

Author: Jung Hoon Woo <jw2853 at columbia.edu>, Yishai Shimoni <ys2559 at columbia.edu>

Maintainer: Jung Hoon Woo <jw2853 at columbia.edu>, Mariano Alvarez <reef103 at gmail.com>

Citation (from within R, enter citation("DeMAND")):

Installation

To install this package, start R (version "4.3") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DeMAND")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DeMAND")
Using DeMAND PDF R Script
Reference Manual PDF
LICENSE Text

Details

biocViews GeneExpression, Network, NetworkEnrichment, Software, StatisticalMethod, SystemsBiology
Version 1.32.0
In Bioconductor since BioC 3.2 (R-3.2) (8.5 years)
License file LICENSE
Depends R (>= 2.14.0), KernSmooth, methods
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DeMAND_1.32.0.tar.gz
Windows Binary DeMAND_1.32.0.zip
macOS Binary (x86_64) DeMAND_1.32.0.tgz
macOS Binary (arm64) DeMAND_1.32.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/DeMAND
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DeMAND
Bioc Package Browser https://code.bioconductor.org/browse/DeMAND/
Package Short Url https://bioconductor.org/packages/DeMAND/
Package Downloads Report Download Stats