DropletUtils

DOI: 10.18129/B9.bioc.DropletUtils    

This is the development version of DropletUtils; for the stable release version, see DropletUtils.

Utilities for Handling Single-Cell Droplet Data

Bioconductor version: Development (3.12)

Provides a number of utility functions for handling single-cell (RNA-seq) data from droplet technologies such as 10X Genomics. This includes data loading from count matrices or molecule information files, identification of cells from empty droplets, removal of barcode-swapped pseudo-cells, and downsampling of the count matrix.

Author: Aaron Lun [aut, cre], Jonathan Griffiths [ctb], Davis McCarthy [ctb]

Maintainer: Aaron Lun <infinite.monkeys.with.keyboards at gmail.com>

Citation (from within R, enter citation("DropletUtils")):

Installation

To install this package, start R (version "4.0") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("DropletUtils")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DropletUtils")

 

HTML R Script Utilities for handling droplet-based single-cell RNA-seq data
PDF   Reference Manual
Text   NEWS

Details

biocViews Coverage, DataImport, GeneExpression, ImmunoOncology, RNASeq, Sequencing, SingleCell, Software, Transcriptomics
Version 1.9.11
In Bioconductor since BioC 3.7 (R-3.5) (2.5 years)
License GPL-3
Depends SingleCellExperiment
Imports utils, stats, methods, Matrix, Rcpp, S4Vectors, BiocParallel, HDF5Array, rhdf5, edgeR, R.utils, dqrng, scuttle
LinkingTo Rcpp, beachmat, Rhdf5lib, BH, dqrng, scuttle
Suggests testthat, beachmat, knitr, BiocStyle, rmarkdown, jsonlite, DropletTestFiles
SystemRequirements C++11, GNU make
Enhances
URL
Depends On Me
Imports Me scCB2
Suggests Me DropletTestFiles, muscData, Nebulosa, splatter
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DropletUtils_1.9.11.tar.gz
Windows Binary DropletUtils_1.9.11.zip
macOS 10.13 (High Sierra) DropletUtils_1.9.11.tgz
Source Repository git clone https://git.bioconductor.org/packages/DropletUtils
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DropletUtils
Package Short Url https://bioconductor.org/packages/DropletUtils/
Package Downloads Report Download Stats

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